ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications

ALKBH1 is a 2-oxoglutarate- and Fe(2+)-dependent dioxygenase responsible for multiple cellular functions. Here, we show that ALKBH1 is involved in biogenesis of 5-hydroxymethyl-2΄-O-methylcytidine (hm(5)Cm) and 5-formyl-2΄-O-methylcytidine (f(5)Cm) at the first position (position 34) of anticodon in...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Kawarada, Layla, Suzuki, Takeo, Ohira, Takayuki, Hirata, Shoji, Miyauchi, Kenjyo, Suzuki, Tsutomu
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499545/
https://ncbi.nlm.nih.gov/pubmed/28472312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx354
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