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Sequence-specific and Shape-selective RNA Recognition by the Human RNA 5-Methylcytosine Methyltransferase NSun6

Human NSun6 is an RNA methyltransferase that catalyzes the transfer of the methyl group from S-adenosyl-l-methionine (SAM) to C72 of tRNA(Thr) and tRNA(Cys). In the current study, we used mass spectrometry to demonstrate that human NSun6 indeed introduces 5-methylcytosine (m(5)C) into tRNA, as expec...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Long, Tao, Li, Jing, Li, Hao, Zhou, Mi, Zhou, Xiao-Long, Liu, Ru-Juan, Wang, En-Duo
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2016
主題:
RNA
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104949/
https://ncbi.nlm.nih.gov/pubmed/27703015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742569
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