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Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes

Notch signaling is involved in the early onset of osteoarthritis. The aim of this study was to investigate the role of Notch signaling changes during proliferation and differentiation of chondrocyte, and to testify the mechanism of MMP-13 regulation by Notch and Runx2 expression changes during osteo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xiao, Di, Bi, Ruiye, Liu, Xianwen, Mei, Jie, Jiang, Nan, Zhu, Songsong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821756/
https://ncbi.nlm.nih.gov/pubmed/31666602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52125-5
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