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Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes

Notch signaling is involved in the early onset of osteoarthritis. The aim of this study was to investigate the role of Notch signaling changes during proliferation and differentiation of chondrocyte, and to testify the mechanism of MMP-13 regulation by Notch and Runx2 expression changes during osteo...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Xiao, Di, Bi, Ruiye, Liu, Xianwen, Mei, Jie, Jiang, Nan, Zhu, Songsong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821756/
https://ncbi.nlm.nih.gov/pubmed/31666602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52125-5
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