Inhibitory effect of midazolam on MMP-9, MMP-1 and MMP-13 expression in PMA-stimulated human chondrocytes via recovery of NF-κB signaling

INTRODUCTION: Midazolam, a benzodiazepine, has a hypnotic effect and is widely used as an intravenous sedative. Past studies have clearly established that midazolam has beneficial effects in attenuating ischemia-reperfusion injury more than other currently used sedative drugs. However, the role of m...

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Autores principales: Wang, Jen-Jui, Huan, Steven Kuan-Hua, Hsieh, Kuo-Hsien, Chou, Hsiu-Chu, Hsiao, George, Jayakumar, Thanasekaran, Sheu, Joen-Rong
Formato: Artigo
Lenguaje:Inglês
Publicado: Termedia Publishing House 2012
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648813/
https://ncbi.nlm.nih.gov/pubmed/23671446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2012.30949
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