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Fumarates target the metabolic-epigenetic interplay of brain-homing T cells in multiple sclerosis
Cell-permeable formulations of metabolites, such as fumaric acid esters, have been used as highly effective immunomodulators in patients with multiple sclerosis and yet their mechanism of action remains elusive. Since fumaric acid esters are metabolites, and cell metabolism is highly intertwined wit...
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| 發表在: | Brain |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821213/ https://ncbi.nlm.nih.gov/pubmed/30698680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy344 |
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