Fumarates target the metabolic-epigenetic interplay of brain-homing T cells in multiple sclerosis

Cell-permeable formulations of metabolites, such as fumaric acid esters, have been used as highly effective immunomodulators in patients with multiple sclerosis and yet their mechanism of action remains elusive. Since fumaric acid esters are metabolites, and cell metabolism is highly intertwined wit...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Brain
Asıl Yazarlar: Ntranos, Achilles, Ntranos, Vasilis, Bonnefil, Valentina, Liu, Jia, Kim-Schulze, Seunghee, He, Ye, Zhu, Yunjiao, Brandstadter, Rachel, Watson, Corey T, Sharp, Andrew J, Katz Sand, Ilana, Casaccia, Patrizia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821213/
https://ncbi.nlm.nih.gov/pubmed/30698680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy344
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