Fumarates target the metabolic-epigenetic interplay of brain-homing T cells in multiple sclerosis

Cell-permeable formulations of metabolites, such as fumaric acid esters, have been used as highly effective immunomodulators in patients with multiple sclerosis and yet their mechanism of action remains elusive. Since fumaric acid esters are metabolites, and cell metabolism is highly intertwined wit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Brain
Egile Nagusiak: Ntranos, Achilles, Ntranos, Vasilis, Bonnefil, Valentina, Liu, Jia, Kim-Schulze, Seunghee, He, Ye, Zhu, Yunjiao, Brandstadter, Rachel, Watson, Corey T, Sharp, Andrew J, Katz Sand, Ilana, Casaccia, Patrizia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821213/
https://ncbi.nlm.nih.gov/pubmed/30698680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy344
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