Fumarates target the metabolic-epigenetic interplay of brain-homing T cells in multiple sclerosis

Cell-permeable formulations of metabolites, such as fumaric acid esters, have been used as highly effective immunomodulators in patients with multiple sclerosis and yet their mechanism of action remains elusive. Since fumaric acid esters are metabolites, and cell metabolism is highly intertwined wit...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Brain
Auteurs principaux: Ntranos, Achilles, Ntranos, Vasilis, Bonnefil, Valentina, Liu, Jia, Kim-Schulze, Seunghee, He, Ye, Zhu, Yunjiao, Brandstadter, Rachel, Watson, Corey T, Sharp, Andrew J, Katz Sand, Ilana, Casaccia, Patrizia
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821213/
https://ncbi.nlm.nih.gov/pubmed/30698680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy344
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires