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Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis
BACKGROUND: Sepsis, a life-threatening organ dysfunction caused by a dysregulated systemic immune response to infection, associates with reduced responsiveness to subsequent infections. How such tolerance is acquired is not well understood but is known to involve epigenetic and transcriptional dysre...
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| 出版年: | Genome Med |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6820973/ https://ncbi.nlm.nih.gov/pubmed/31665078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0674-2 |
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