Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis

BACKGROUND: Sepsis, a life-threatening organ dysfunction caused by a dysregulated systemic immune response to infection, associates with reduced responsiveness to subsequent infections. How such tolerance is acquired is not well understood but is known to involve epigenetic and transcriptional dysre...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Lorente-Sorolla, Clara, Garcia-Gomez, Antonio, Català-Moll, Francesc, Toledano, Víctor, Ciudad, Laura, Avendaño-Ortiz, José, Maroun-Eid, Charbel, Martín-Quirós, Alejandro, Martínez-Gallo, Mónica, Ruiz-Sanmartín, Adolfo, del Campo, Álvaro García, Ferrer-Roca, Ricard, Ruiz-Rodriguez, Juan Carlos, Álvarez-Errico, Damiana, López-Collazo, Eduardo, Ballestar, Esteban
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820973/
https://ncbi.nlm.nih.gov/pubmed/31665078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0674-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados