CD4 Incorporation into HIV-1 Viral Particles Exposes Envelope Epitopes Recognized by CD4-Induced Antibodies

CD4 downregulation on infected cells is a highly conserved function of primate lentiviruses. It has been shown to positively impact viral replication by a variety of mechanisms, including enhanced viral release and infectivity, decrease of cell reinfection, and protection from antibody-dependent cel...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Ding, Shilei, Gasser, Romain, Gendron-Lepage, Gabrielle, Medjahed, Halima, Tolbert, William D., Sodroski, Joseph, Pazgier, Marzena, Finzi, Andrés
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819941/
https://ncbi.nlm.nih.gov/pubmed/31484748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01403-19
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