Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity

Anti-HIV-1 envelope glycoprotein (Env) antibodies without broadly neutralizing activity correlated with protection in the RV144 clinical trial, stimulating interest in other protective mechanisms involving antibodies, such as antibody-dependent cell-mediated cytotoxicity (ADCC). Env epitopes targete...

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Bibliografische gegevens
Hoofdauteurs: Veillette, Maxime, Désormeaux, Anik, Medjahed, Halima, Gharsallah, Nour-Elhouda, Coutu, Mathieu, Baalwa, Joshua, Guan, Yongjun, Lewis, George, Ferrari, Guido, Hahn, Beatrice H., Haynes, Barton F., Robinson, James E., Kaufmann, Daniel E., Bonsignori, Mattia, Sodroski, Joseph, Finzi, Andrés
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958102/
https://ncbi.nlm.nih.gov/pubmed/24352444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03230-13
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