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Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

HIV-1 envelope glycoproteins (Env) mediate viral entry into target cells and are essential to the infectious cycle. Understanding how those glycoproteins are able to fuel the fusion process through their conformational changes could lead to the design of better, more effective immunogens for vaccine...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Veillette, Maxime, Coutu, Mathieu, Richard, Jonathan, Batraville, Laurie-Anne, Désormeaux, Anik, Roger, Michel, Finzi, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828074/
https://ncbi.nlm.nih.gov/pubmed/25286159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51995
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