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Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

HIV-1 envelope glycoproteins (Env) mediate viral entry into target cells and are essential to the infectious cycle. Understanding how those glycoproteins are able to fuel the fusion process through their conformational changes could lead to the design of better, more effective immunogens for vaccine...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Veillette, Maxime, Coutu, Mathieu, Richard, Jonathan, Batraville, Laurie-Anne, Désormeaux, Anik, Roger, Michel, Finzi, Andrés
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828074/
https://ncbi.nlm.nih.gov/pubmed/25286159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51995
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