Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

HIV-1 envelope glycoproteins (Env) mediate viral entry into target cells and are essential to the infectious cycle. Understanding how those glycoproteins are able to fuel the fusion process through their conformational changes could lead to the design of better, more effective immunogens for vaccine...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Veillette, Maxime, Coutu, Mathieu, Richard, Jonathan, Batraville, Laurie-Anne, Désormeaux, Anik, Roger, Michel, Finzi, Andrés
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2014
Fag:
Infectious Diseases
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828074/
https://ncbi.nlm.nih.gov/pubmed/25286159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51995
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