The HIV-1 gp120 CD4-Bound Conformation Is Preferentially Targeted by Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Sera from HIV-1-Infected Individuals

Recent studies have linked antibody Fc-mediated effector functions with protection or control of human immunodeficiency type 1 (HIV-1) and simian immunodeficiency (SIV) infections. Interestingly, the presence of antibodies with potent antibody-dependent cellular cytotoxicity (ADCC) activity in the T...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Veillette, Maxime, Coutu, Mathieu, Richard, Jonathan, Batraville, Laurie-Anne, Dagher, Olina, Bernard, Nicole, Tremblay, Cécile, Kaufmann, Daniel E., Roger, Michel, Finzi, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301108/
https://ncbi.nlm.nih.gov/pubmed/25339767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02868-14
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