HIV-1 gp120 envelope glycoprotein determinants for cytokine burst in human monocytes

The first step of HIV infection involves the interaction of the gp120 envelope glycoprotein to its receptor CD4, mainly expressed on CD4(+) T cells. Besides its role on HIV-1 entry, the gp120 has been shown to be involved in the production of IL-1, IL-6, CCL20 and other innate response cytokines by...

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Bibliographic Details
Published in:PLoS One
Main Authors: Levast, Benoît, Barblu, Lucie, Coutu, Mathieu, Prévost, Jérémie, Brassard, Nathalie, Peres, Adam, Stegen, Camille, Madrenas, Joaquín, Kaufmann, Daniel E., Finzi, Andrés
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367833/
https://ncbi.nlm.nih.gov/pubmed/28346521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174550
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