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HIV-1 gp120 envelope glycoprotein determinants for cytokine burst in human monocytes

The first step of HIV infection involves the interaction of the gp120 envelope glycoprotein to its receptor CD4, mainly expressed on CD4(+) T cells. Besides its role on HIV-1 entry, the gp120 has been shown to be involved in the production of IL-1, IL-6, CCL20 and other innate response cytokines by...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Levast, Benoît, Barblu, Lucie, Coutu, Mathieu, Prévost, Jérémie, Brassard, Nathalie, Peres, Adam, Stegen, Camille, Madrenas, Joaquín, Kaufmann, Daniel E., Finzi, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367833/
https://ncbi.nlm.nih.gov/pubmed/28346521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174550
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