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Probing the Basis of α-Synuclein Aggregation by Comparing Simulations to Single-Molecule Experiments
Intrinsically disordered proteins often play an important role in protein aggregation. However, it is challenging to determine the structures and interactions that drive the early stages of aggregation because they are transient and obscured in a heterogeneous mixture of disordered states. Even comp...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6818160/ https://ncbi.nlm.nih.gov/pubmed/31477241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.08.013 |
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