A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers

Mapping the chromatin occupancy of transcription factors (TFs) is a key step in deciphering developmental transcriptional programs. Here we use biotinylated knockin alleles of seven key cardiac TFs (GATA4, NKX2-5, MEF2A, MEF2C, SRF, TBX5, TEAD1) to sensitively and reproducibly map their genome-wide...

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Pubblicato in:Nat Commun
Autori principali: Akerberg, Brynn N., Gu, Fei, VanDusen, Nathan J., Zhang, Xiaoran, Dong, Rui, Li, Kai, Zhang, Bing, Zhou, Bin, Sethi, Isha, Ma, Qing, Wasson, Lauren, Wen, Tong, Liu, Jinhua, Dong, Kunzhe, Conlon, Frank L., Zhou, Jiliang, Yuan, Guo-Cheng, Zhou, Pingzhu, Pu, William T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817842/
https://ncbi.nlm.nih.gov/pubmed/31659164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12812-3
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