A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers

Mapping the chromatin occupancy of transcription factors (TFs) is a key step in deciphering developmental transcriptional programs. Here we use biotinylated knockin alleles of seven key cardiac TFs (GATA4, NKX2-5, MEF2A, MEF2C, SRF, TBX5, TEAD1) to sensitively and reproducibly map their genome-wide...

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Publicado no:Nat Commun
Main Authors: Akerberg, Brynn N., Gu, Fei, VanDusen, Nathan J., Zhang, Xiaoran, Dong, Rui, Li, Kai, Zhang, Bing, Zhou, Bin, Sethi, Isha, Ma, Qing, Wasson, Lauren, Wen, Tong, Liu, Jinhua, Dong, Kunzhe, Conlon, Frank L., Zhou, Jiliang, Yuan, Guo-Cheng, Zhou, Pingzhu, Pu, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817842/
https://ncbi.nlm.nih.gov/pubmed/31659164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12812-3
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