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CASAAV: a CRISPR based platform for rapid dissection of gene function in vivo
In vivo loss-of-function studies are currently limited by the need for appropriate conditional knockout alleles. CRISPR/Cas9 is a powerful tool commonly used to induce loss-of-function mutations in vitro. However, the CRISPR components have been difficult to deploy in vivo. To address this problem,...
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| Publicado no: | Curr Protoc Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654550/ https://ncbi.nlm.nih.gov/pubmed/28967995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpmb.46 |
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