Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits

Genome-wide association studies (GWASs) have identified thousands of genetic loci associated with cardiometabolic traits including type 2 diabetes (T2D), lipid levels, body fat distribution, and adiposity, although most causal genes remain unknown. We used subcutaneous adipose tissue RNA-seq data fr...

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Gepubliceerd in:Am J Hum Genet
Hoofdauteurs: Raulerson, Chelsea K., Ko, Arthur, Kidd, John C., Currin, Kevin W., Brotman, Sarah M., Cannon, Maren E., Wu, Ying, Spracklen, Cassandra N., Jackson, Anne U., Stringham, Heather M., Welch, Ryan P., Fuchsberger, Christian, Locke, Adam E., Narisu, Narisu, Lusis, Aldons J., Civelek, Mete, Furey, Terrence S., Kuusisto, Johanna, Collins, Francis S., Boehnke, Michael, Scott, Laura J., Lin, Dan-Yu, Love, Michael I., Laakso, Markku, Pajukanta, Päivi, Mohlke, Karen L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817527/
https://ncbi.nlm.nih.gov/pubmed/31564431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.09.001
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