Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

Increased adiposity is a hallmark of obesity and overweight, which affect 2.2 billion people world-wide. Understanding the genetic and molecular mechanisms that underlie obesity-related phenotypes can help to improve treatment options and drug development. Here we perform promoter Capture Hi–C in hu...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Pan, David Z., Garske, Kristina M., Alvarez, Marcus, Bhagat, Yash V., Boocock, James, Nikkola, Elina, Miao, Zong, Raulerson, Chelsea K., Cantor, Rita M., Civelek, Mete, Glastonbury, Craig A., Small, Kerrin S., Boehnke, Michael, Lusis, Aldons J., Sinsheimer, Janet S., Mohlke, Karen L., Laakso, Markku, Pajukanta, Päivi, Ko, Arthur
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904163/
https://ncbi.nlm.nih.gov/pubmed/29666371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03554-9
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk