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The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation

The Su(var)3–9, enhancer of zeste, and trithorax (SET) and really interesting new gene (RING) finger–associated (SRA) protein domain is conserved across bacteria and eukaryota and coordinates extrahelical or “flipped” DNA bases. A functional SRA domain is required for ubiquitin-like with PHD and RIN...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Vaughan, Robert M., Rothbart, Scott B., Dickson, Bradley M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816099/
https://ncbi.nlm.nih.gov/pubmed/31481468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010160
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