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Depletion of Mitochondrial DNA in Differentiated Retinal Pigment Epithelial Cells

We investigated the effects of treating differentiated retinal pigment epithelial (RPE) cells with didanosine (ddI), which is associated with retinopathy in individuals with HIV/AIDS. We hypothesized that such treatment would cause depletion of mitochondrial DNA and provide insight into the conseque...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Hu, Xinqian, Calton, Melissa A., Tang, Shibo, Vollrath, Douglas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814719/
https://ncbi.nlm.nih.gov/pubmed/31653972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51761-1
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