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Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells

Glutathione (GSH) protects against oxidative damage in many tissues, including retinal pigment epithelium (RPE). Oxidative stress-mediated senescence and death of RPE and subsequent death of photoreceptors have been observed in age-related macular degeneration (AMD). Although the consequences of GSH...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Sun, Yun, Zheng, Yingfeng, Wang, Chunxiao, Liu, Yizhi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037763/
https://ncbi.nlm.nih.gov/pubmed/29988039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0794-4
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