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Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells
Glutathione (GSH) protects against oxidative damage in many tissues, including retinal pigment epithelium (RPE). Oxidative stress-mediated senescence and death of RPE and subsequent death of photoreceptors have been observed in age-related macular degeneration (AMD). Although the consequences of GSH...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037763/ https://ncbi.nlm.nih.gov/pubmed/29988039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0794-4 |
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