Retinal pigment epithelial cells undergoing mitotic catastrophe are vulnerable to autophagy inhibition

The increased mitochondrial DNA damage leads to altered functional capacities of retinal pigment epithelial (RPE) cells. A previous study showed the increased autophagy in RPE cells caused by low concentrations of rotenone, a selective inhibitor of mitochondrial complex I. However, the mechanism by...

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Sonraí Bibleagrafaíochta
Foilsithe in:Cell Death Dis
Main Authors: Lee, S Y, Oh, J S, Rho, J H, Jeong, N Y, Kwon, Y H, Jeong, W J, Ryu, W Y, Ahn, H B, Park, W C, Rho, S H, Yoon, Y G, Jeong, S-Y, Choi, Y H, Kim, H Y, Yoo, Y H
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2014
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611738/
https://ncbi.nlm.nih.gov/pubmed/24967965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.266
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