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Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties

Retinal pigment epithelium (RPE) acts as an outer blood–retinal barrier that limits the access of circulating xenobiotics to the eye. In addition, the RPE limits posterior elimination of intravitreally injected drugs to circulation. Thus, permeation in the RPE has a significant effect on ocular phar...

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Foilsithe in:Pharmaceutics
Main Authors: Hellinen, Laura, Pirskanen, Lea, Tengvall-Unadike, Unni, Urtti, Arto, Reinisalo, Mika
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722654/
https://ncbi.nlm.nih.gov/pubmed/31412689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11080412
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