CXCR5(+)CD8(+) T cells are a distinct functional subset with antitumor activity

CXCR5 mediates homing of both B and follicular helper T (T(FH)) cells into follicles of secondary lymphoid organs. We found that CXCR5(+)CD8(+) T cells are present in human tonsils and follicular lymphoma, inhibit T(FH)-mediated B-cell differentiation, and exhibit strong cytotoxic activity. Consiste...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Leukemia
Hlavní autoři: Chu, Fuliang, Li, Haiyan S., Liu, Xindong, Cao, Jingjing, Ma, Wencai, Ma, Ying, Weng, Jinsheng, Zhu, Zheng, Cheng, Xiaoyun, Wang, Zhiqiang, Liu, Jingwei, Jiang, Zi Yang, Luong, Amber, Peng, Weiyi, Wang, Jing, Balakrishnan, Kumudha, Yee, Cassian, Dong, Chen, Davis, Richard Eric, Watowich, Stephanie S., Neelapu, Sattva S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814517/
https://ncbi.nlm.nih.gov/pubmed/31028278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0464-2
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky