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Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the anti-tumor efficacy of dendritic cells()
Despite the potent ability of dendritic cells (DCs) to stimulate lymphocyte responses and host immunity, granulocyte-macrophage colony-stimulating factor (GM-CSF)-derived DCs (GM-DCs) used as antitumor vaccines have demonstrated relatively modest success in cancer immunotherapy. We found that inject...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5061503/ https://ncbi.nlm.nih.gov/pubmed/27678219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf3957 |
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