CXCR5(+)CD8(+) T cells are a distinct functional subset with antitumor activity

CXCR5 mediates homing of both B and follicular helper T (T(FH)) cells into follicles of secondary lymphoid organs. We found that CXCR5(+)CD8(+) T cells are present in human tonsils and follicular lymphoma, inhibit T(FH)-mediated B-cell differentiation, and exhibit strong cytotoxic activity. Consiste...

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Dades bibliogràfiques
Publicat a:Leukemia
Autors principals: Chu, Fuliang, Li, Haiyan S., Liu, Xindong, Cao, Jingjing, Ma, Wencai, Ma, Ying, Weng, Jinsheng, Zhu, Zheng, Cheng, Xiaoyun, Wang, Zhiqiang, Liu, Jingwei, Jiang, Zi Yang, Luong, Amber, Peng, Weiyi, Wang, Jing, Balakrishnan, Kumudha, Yee, Cassian, Dong, Chen, Davis, Richard Eric, Watowich, Stephanie S., Neelapu, Sattva S.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814517/
https://ncbi.nlm.nih.gov/pubmed/31028278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0464-2
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