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Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs
O-Linked α-N-acetylgalactosamine (O-Gal-NAc) glycans constitute a major part of the human glycome. They are difficult to study because of the complex interplay of 20 distinct glycosyltransferase isoenzymes that initiate this form of glycosylation, the polypeptide N-acetylgalactosaminyl-transferases...
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| Publicado en: | J Am Chem Soc |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6813768/ https://ncbi.nlm.nih.gov/pubmed/31373799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b04695 |
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