Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity

UDP-GalNAc:polypeptide α-N-acetylgalactosaminyltransferases (GalNAc-Ts) constitute a family of up to 20 transferases that initiate mucin-type O-glycosylation. The transferases are structurally composed of catalytic and lectin domains. Two modes have been identified for the selection of glycosylation...

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Detalhes bibliográficos
Main Authors: Pedersen, Johannes W., Bennett, Eric P., Schjoldager, Katrine T.-B. G., Meldal, Morten, Holmér, Andreas P., Blixt, Ola, Cló, Emiliano, Levery, Steven B., Clausen, Henrik, Wandall, Hans H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173194/
https://ncbi.nlm.nih.gov/pubmed/21768105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.273722
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