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Development of Isoform-specific Sensors of Polypeptide GalNAc-transferase Activity
Humans express up to 20 isoforms of GalNAc-transferase (herein T1–T20) that localize to the Golgi apparatus and initiate O-glycosylation. Regulation of this enzyme family affects a vast array of proteins transiting the secretory pathway and diseases arise upon misregulation of specific isoforms. Sur...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215235/ https://ncbi.nlm.nih.gov/pubmed/25225288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599563 |
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