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Activation of Sigma 1 Receptor Extends Survival of Cones and Improves Visual Acuity in a Murine Model of Retinitis Pigmentosa
PURPOSE: Retinitis pigmentosa (RP), a retinal photoreceptor degeneration, typically affects rod function and subsequently cones. Activation of sigma 1 receptor (Sig1R) has been shown to preserve cone function through 6 weeks in the rd10 mouse model of RP, when mice were treated systemically with the...
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| Published in: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Association for Research in Vision and Ophthalmology
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6808049/ https://ncbi.nlm.nih.gov/pubmed/31639826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-27709 |
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