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Role of Sigma 1 Receptor in Retinal Degeneration of the Ins2(Akita/+) Murine Model of Diabetic Retinopathy
PURPOSE: Sigma receptor 1 (Sigma1R), a nonopioid putative molecular chaperone, has neuroprotective properties in retina. This study sought to determine whether delaying administration of (+)-pentazocine, a high-affinity Sigma1R ligand after onset of diabetes in Ins2(Akita/+) diabetic mice would affo...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4884059/ https://ncbi.nlm.nih.gov/pubmed/27206247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18995 |
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