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Role of Sigma 1 Receptor in Retinal Degeneration of the Ins2(Akita/+) Murine Model of Diabetic Retinopathy

PURPOSE: Sigma receptor 1 (Sigma1R), a nonopioid putative molecular chaperone, has neuroprotective properties in retina. This study sought to determine whether delaying administration of (+)-pentazocine, a high-affinity Sigma1R ligand after onset of diabetes in Ins2(Akita/+) diabetic mice would affo...

詳細記述

保存先:
書誌詳細
出版年:Invest Ophthalmol Vis Sci
主要な著者: Wang, Jing, Cui, Xuezhi, Roon, Penny, Smith, Sylvia B.
フォーマット: Artigo
言語:Inglês
出版事項: The Association for Research in Vision and Ophthalmology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884059/
https://ncbi.nlm.nih.gov/pubmed/27206247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18995
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