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Oncolytic adenovirus programmed by synthetic gene circuit for cancer immunotherapy
Improving efficacy of oncolytic virotherapy remains challenging due to difficulty increasing specificity and immune responses against cancer and limited understanding of its population dynamics. Here, we construct programmable and modular synthetic gene circuits to control adenoviral replication and...
Gorde:
| Argitaratua izan da: | Nat Commun |
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| Egile Nagusiak: | , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6805884/ https://ncbi.nlm.nih.gov/pubmed/31641136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12794-2 |
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