Chronic nigral neuromodulation aggravates behavioral deficits and synaptic changes in an α-synuclein based rat model for Parkinson’s disease

Aggregation of alpha-synuclein (α-SYN) is the pathological hallmark of several diseases named synucleinopathies, including Parkinson’s disease (PD), which is the most common neurodegenerative motor disorder. Alpha-SYN has been linked to synaptic function both in physiological and pathological condit...

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Detalles Bibliográficos
Publicado en:Acta Neuropathol Commun
Main Authors: Torre-Muruzabal, Teresa, Devoght, Jens, Van den Haute, Chris, Brône, Bert, Van der Perren, Anke, Baekelandt, Veerle
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805517/
https://ncbi.nlm.nih.gov/pubmed/31640762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0814-3
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