Development of an Alpha-synuclein Based Rat Model for Parkinson's Disease via Stereotactic Injection of a Recombinant Adeno-associated Viral Vector

In order to study the molecular pathways of Parkinson's disease (PD) and to develop novel therapeutic strategies, scientific investigators rely on animal models. The identification of PD-associated genes has led to the development of genetic PD models. Most transgenic α-SYN mouse models develop...

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Vydáno v:J Vis Exp
Hlavní autoři: Van der Perren, Anke, Casteels, Cindy, Van Laere, Koen, Gijsbers, Rik, Van den Haute, Chris, Baekelandt, Veerle
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2016
Témata:
Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828209/
https://ncbi.nlm.nih.gov/pubmed/26967677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53670
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