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2058 miRNA manipulation to improve CFTR correction in cystic fibrosis
OBJECTIVES/SPECIFIC AIMS: CFTR is the mutant protein that causes cystic fibrosis (CF), a fatal respiratory diseases affecting 1 in 3500 children. CFTR modulators are small molecules that directly address mutant CFTR function. Improving correction of the F508del CFTR mutation (affecting 90% of CF pat...
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| Udgivet i: | J Clin Transl Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cambridge University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6804970/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.96 |
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