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Fixing cystic fibrosis by correcting CFTR domain assembly
For cystic fibrosis (CF) patients most therapies focus on alleviating the disease symptoms. Yet the cellular basis of the disease has been well studied; mutations in the CF gene can impair folding, secretion, cell surface stability, and/or function of the CFTR chloride channel. Correction of these b...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471238/ https://ncbi.nlm.nih.gov/pubmed/23071149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201208083 |
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