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Cooperative Assembly and Misfolding of CFTR Domains In Vivo
The cystic fibrosis transmembrane conductance regulator (CFTR) architecture consists of two membrane spanning domains (MSD1 and -2), two nucleotide binding domains (NBD1 and -2), and a regulatory (R) domain. Several point mutations lead to the channel misprocessing, with limited structural perturbat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663924/ https://ncbi.nlm.nih.gov/pubmed/19176754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0950 |
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