Загрузка...
CFTR: folding, misfolding and correcting the ΔF508 conformational defect
Cystic fibrosis (CF), the most common lethal genetic disease in the Caucasian population, is caused by loss-of-function mutations of the CF transmembrane conductance regulator (CFTR), a cyclic AMP-regulated plasma membrane chloride channel. The most common mutation, deletion of phenylalanine 508 (ΔF...
Сохранить в:
| Главные авторы: | , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643519/ https://ncbi.nlm.nih.gov/pubmed/22138491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.10.003 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|