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Targeted therapies to improve CFTR function in cystic fibrosis

Cystic fibrosis is the most common genetically determined, life-limiting disorder in populations of European ancestry. The genetic basis of cystic fibrosis is well established to be mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that codes for an apical membrane chl...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Brodlie, Malcolm, Haq, Iram J., Roberts, Katie, Elborn, J. Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582929/
https://ncbi.nlm.nih.gov/pubmed/26403534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0223-6
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