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Targeted therapies to improve CFTR function in cystic fibrosis

Cystic fibrosis is the most common genetically determined, life-limiting disorder in populations of European ancestry. The genetic basis of cystic fibrosis is well established to be mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that codes for an apical membrane chl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genome Med
Hauptverfasser: Brodlie, Malcolm, Haq, Iram J., Roberts, Katie, Elborn, J. Stuart
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582929/
https://ncbi.nlm.nih.gov/pubmed/26403534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0223-6
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