Antimalarial Activity of Human Group IIA Secreted Phospholipase A(2) in Relation to Enzymatic Hydrolysis of Oxidized Lipoproteins

The level of human group IIA secreted phospholipase A(2) (hGIIA sPLA(2)) is increased in the plasma of malaria patients, but its role is unknown. In parasite culture with normal plasma, hGIIA is inactive against Plasmodium falciparum, contrasting with hGIIF, hGV, and hGX sPLA(2)s, which readily hydr...

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Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Dacheux, Mélanie, Sinou, Véronique, Payré, Christine, Jeammet, Louise, Parzy, Daniel, Grellier, Philippe, Deregnaucourt, Christiane, Lambeau, Gérard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2019
Aiheet:
Molecular Pathogenesis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803347/
https://ncbi.nlm.nih.gov/pubmed/31405958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00556-19
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