Antimalarial Activity of Human Group IIA Secreted Phospholipase A(2) in Relation to Enzymatic Hydrolysis of Oxidized Lipoproteins

The level of human group IIA secreted phospholipase A(2) (hGIIA sPLA(2)) is increased in the plasma of malaria patients, but its role is unknown. In parasite culture with normal plasma, hGIIA is inactive against Plasmodium falciparum, contrasting with hGIIF, hGV, and hGX sPLA(2)s, which readily hydr...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Dacheux, Mélanie, Sinou, Véronique, Payré, Christine, Jeammet, Louise, Parzy, Daniel, Grellier, Philippe, Deregnaucourt, Christiane, Lambeau, Gérard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803347/
https://ncbi.nlm.nih.gov/pubmed/31405958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00556-19
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