Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus Entry by a Specific PF-68742 Stereoisomer

Human immunodeficiency virus (HIV-1) entry into cells is mediated by the viral envelope glycoprotein (Env) trimer, which consists of three gp120 exterior glycoproteins and three gp41 transmembrane glycoproteins. When gp120 binds sequentially to the receptors CD4 and CCR5 on the target cell, the meta...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Virol
Κύριοι συγγραφείς: Zhao, Connie, Princiotto, Amy M., Nguyen, Hanh T., Zou, Shitao, Zhao, Meiqing Lily, Zhang, Shijian, Herschhorn, Alon, Farrell, Mark, Pahil, Karanbir, Melillo, Bruno, Sambasivarao, Somisetti V., Abrams, Cameron, Smith, Amos B., Madani, Navid, Sodroski, Joseph
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2019
Θέματα:
Vaccines and Antiviral Agents
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803283/
https://ncbi.nlm.nih.gov/pubmed/31391272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01197-19
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