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Reactivity of N3-Methyl-2′-Deoxyadenosine in Nucleosome Core Particles
[Image: see text] N3-Methyl-2′-deoxyadenosine (MdA) is the major dA methylation product in duplex DNA. MdA blocks DNA replication and undergoes depurination at significantly higher rates than the native nucleotide from which it is derived. Recent reports on the effects of the nucleosome core particl...
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| Gepubliceerd in: | Chem Res Toxicol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical
Society
2019
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6803048/ https://ncbi.nlm.nih.gov/pubmed/31565933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00299 |
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