Targeting Nuclear Exporter Protein XPO1/CRM1 in Gastric Cancer

Gastric cancer remains an unmet clinical problem in urgent need of newer and effective treatments. Here we show that the nuclear export protein, Exportin 1 (XPO1, chromosome region maintenance 1 or CRM1), is a promising molecular target in gastric cancer. We demonstrate significant overexpression of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sexton, Rachel, Mahdi, Zaid, Chaudhury, Rahman, Beydoun, Rafic, Aboukameel, Amro, Khan, Husain Y., Baloglu, Erkan, Senapedis, William, Landesman, Yosef, Tesfaye, Anteneh, Kim, Steve, Philip, Philip A., Azmi, Asfar S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801932/
https://ncbi.nlm.nih.gov/pubmed/31569391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20194826
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